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Journal of Clinical Microbiology, February 2000, p. 872-873, Vol. 38, No. 2
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Reliability of the MB/BacT System for Testing Susceptibility of Mycobacterium tuberculosis Complex Isolates to Antituberculous Drugs

Francesca Brunello and Roberta Fontana*

Dipartimento di Patologia, Sezione di Microbiologia, and Servizio di Microbiologia dell'Azienda Ospedaliera di Verona, Verona, Italy

Received 3 August 1999/Returned for modification 21 September 1999/Accepted 17 November 1999

The susceptibility of 115 Mycobacterium tuberculosis complex clinical isolates to isoniazid, streptomycin, ethambutol, and rifampin was assessed by the MB/BacT and BACTEC 460TB systems. The correlation between the two tests was 98.3% for isoniazid, 100% for streptomycin and rifampin, and 95.8% for ethambutol. Turnaround times for antimicrobial susceptibility testing ranged from 5 to 11 days (median, 8.5 days) for MB/BacT and from 4 to 8 days (median, 6 days) for BACTEC 460TB.

* Corresponding author. Mailing address: Università di Verona, Dipartimento di Patologia, Sezione di Microbiologia, Strada le Grazie 8, 37100 Verona, Italy. Phone: 0039-45-8098191. Fax: 0039-45-584606. E-mail: FONTANAR{at}BORGOROMA.UNIVR.IT.

Journal of Clinical Microbiology, February 2000, p. 872-873, Vol. 38, No. 2
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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