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Journal of Clinical Microbiology, March 2000, p. 1008-1015, Vol. 38, No. 3
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Multilocus Sequence Typing for Characterization of Methicillin-Resistant and Methicillin-Susceptible Clones of Staphylococcus aureus

Mark C. Enright,1,* Nicholas P. J. Day,2 Catrin E. Davies,2 Sharon J. Peacock,2,3 and Brian G. Spratt1

Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, Oxford University, Oxford OX1 3FY,1 and Wellcome Trust Centre for Clinical Tropical Medicine, Nuffield Department of Medicine,2 and Department of Pathology and Bacteriology,3 Oxford University, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom

Received 22 September 1999/Accepted 15 December 1999

A multilocus sequence typing (MLST) scheme has been developed for Staphylococcus aureus. The sequences of internal fragments of seven housekeeping genes were obtained for 155 S. aureus isolates from patients with community-acquired and hospital-acquired invasive disease in the Oxford, United Kingdom, area. Fifty-three different allelic profiles were identified, and 17 of these were represented by at least two isolates. The MLST scheme was highly discriminatory and was validated by showing that pairs of isolates with the same allelic profile produced very similar SmaI restriction fragment patterns by pulsed-field gel electrophoresis. All 22 isolates with the most prevalent allelic profile were methicillin-resistant S. aureus (MRSA) isolates and had allelic profiles identical to that of a reference strain of the epidemic MRSA clone 16 (EMRSA-16). Four MRSA isolates that were identical in allelic profile to the other major epidemic MRSA clone prevalent in British hospitals (clone EMRSA-15) were also identified. The majority of isolates (81%) were methicillin-susceptible S. aureus (MSSA) isolates, and seven MSSA clones included five or more isolates. Three of the MSSA clones included at least five isolates from patients with community-acquired invasive disease and may represent virulent clones with an increased ability to cause disease in otherwise healthy individuals. The most prevalent MSSA clone (17 isolates) was very closely related to EMRSA-16, and the success of the latter clone at causing disease in hospitals may be due to its emergence from a virulent MSSA clone that was already a major cause of invasive disease in both the community and hospital settings. MLST provides an unambiguous method for assigning MRSA and MSSA isolates to known clones or assigning them as novel clones via the Internet.

* Corresponding author. Mailing address: Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, South Parks Rd., University of Oxford, Oxford OX1 3FY, United Kingdom. Phone: 44 1865-281274. Fax: 44 1865-281891. E-mail. mark.enright{at}ceid.ox.ac.uk.

Journal of Clinical Microbiology, March 2000, p. 1008-1015, Vol. 38, No. 3
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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  • Luczak-Kadlubowska, A., Sulikowska, A., Empel, J., Piasecka, A., Orczykowska, M., Kozinska, A., Hryniewicz, W. (2008). Countrywide Molecular Survey of Methicillin-Resistant Staphylococcus aureus Strains in Poland. J. Clin. Microbiol. 46: 2930-2937 [Abstract] [Full Text]  
  • Goering, R. V., Shawar, R. M., Scangarella, N. E., O'Hara, F. P., Amrine-Madsen, H., West, J. M., Dalessandro, M., Becker, J. A., Walsh, S. L., Miller, L. A., van Horn, S. F., Thomas, E. S., Twynholm, M. E. (2008). Molecular Epidemiology of Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Isolates from Global Clinical Trials. J. Clin. Microbiol. 46: 2842-2847 [Abstract] [Full Text]  
  • Ikawaty, R., Willems, R. J. L., Box, A. T. A., Verhoef, J., Fluit, A. C. (2008). Novel Multiple-Locus Variable-Number Tandem-Repeat Analysis Method for Rapid Molecular Typing of Human Staphylococcus aureus. J. Clin. Microbiol. 46: 3147-3151 [Abstract] [Full Text]  
  • Fan, H., Li, N., Wang, L. (2008). Three cases of community-associated meticillin-resistant Staphylococcus aureus infection in China. J Med Microbiol 57: 1178-1179 [Full Text]  
  • Parsonnet, J., Goering, R. V., Hansmann, M. A., Jones, M. B., Ohtagaki, K., Davis, C. C., Totsuka, K. (2008). Prevalence of Toxic Shock Syndrome Toxin 1 (TSST-1)-Producing Strains of Staphylococcus aureus and Antibody to TSST-1 among Healthy Japanese Women. J. Clin. Microbiol. 46: 2731-2738 [Abstract] [Full Text]  
  • Peleg, A. Y., Seifert, H., Paterson, D. L. (2008). Acinetobacter baumannii: Emergence of a Successful Pathogen. Clin. Microbiol. Rev. 21: 538-582 [Abstract] [Full Text]  
  • Sung, J. M.-L., Lloyd, D. H., Lindsay, J. A. (2008). Staphylococcus aureus host specificity: comparative genomics of human versus animal isolates by multi-strain microarray. Microbiology 154: 1949-1959 [Abstract] [Full Text]  
  • Ruimy, R., Maiga, A., Armand-Lefevre, L., Maiga, I., Diallo, A., Koumare, A. K., Ouattara, K., Soumare, S., Gaillard, K., Lucet, J.-C., Andremont, A., Feil, E. J. (2008). The Carriage Population of Staphylococcus aureus from Mali Is Composed of a Combination of Pandemic Clones and the Divergent Panton-Valentine Leukocidin-Positive Genotype ST152. J. Bacteriol. 190: 3962-3968 [Abstract] [Full Text]  
  • Glikman, D., Siegel, J. D., David, M. Z., Okoro, N. M., Boyle-Vavra, S., Dowell, M. L., Daum, R. S. (2008). Complex Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus Isolates From Children With Cystic Fibrosis in the Era of Epidemic Community-Associated Methicillin-Resistant S aureus. Chest 133: 1381-1387 [Abstract] [Full Text]  
  • Sing, A., Tuschak, C., Hormansdorfer, S. (2008). Methicillin-Resistant Staphylococcus aureus in a Family and Its Pet Cat. NEJM 358: 1200-1201 [Full Text]  
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  • Collery, M. M., Smyth, D. S., Twohig, J. M., Shore, A. C., Coleman, D. C., Smyth, C. J. (2008). Molecular typing of nasal carriage isolates of Staphylococcus aureus from an Irish university student population based on toxin gene PCR, agr locus types and multiple locus, variable number tandem repeat analysis. J Med Microbiol 57: 348-358 [Abstract] [Full Text]  
  • Petrelli, D., Repetto, A., D'Ercole, S., Rombini, S., Ripa, S., Prenna, M., Vitali, L. A. (2008). Analysis of meticillin-susceptible and meticillin-resistant biofilm-forming Staphylococcus aureus from catheter infections isolated in a large Italian hospital. J Med Microbiol 57: 364-372 [Abstract] [Full Text]  
  • Diep, B. A., Chambers, H. F., Graber, C. J., Szumowski, J. D., Miller, L. G., Han, L. L., Chen, J. H., Lin, F., Lin, J., Phan, T. H., Carleton, H. A., McDougal, L. K., Tenover, F. C., Cohen, D. E., Mayer, K. H., Sensabaugh, G. F., Perdreau-Remington, F. (2008). Emergence of Multidrug-Resistant, Community-Associated, Methicillin-Resistant Staphylococcus aureus Clone USA300 in Men Who Have Sex with Men. ANN INTERN MED 148: 249-257 [Abstract] [Full Text]  
  • Noto, M. J., Kreiswirth, B. N., Monk, A. B., Archer, G. L. (2008). Gene Acquisition at the Insertion Site for SCCmec, the Genomic Island Conferring Methicillin Resistance in Staphylococcus aureus. J. Bacteriol. 190: 1276-1283 [Abstract] [Full Text]  
  • Strommenger, B., Braulke, C., Heuck, D., Schmidt, C., Pasemann, B., Nubel, U., Witte, W. (2008). spa Typing of Staphylococcus aureus as a Frontline Tool in Epidemiological Typing. J. Clin. Microbiol. 46: 574-581 [Abstract] [Full Text]  
  • Zhu, W., Clark, N. C., McDougal, L. K., Hageman, J., McDonald, L. C., Patel, J. B. (2008). Vancomycin-Resistant Staphylococcus aureus Isolates Associated with Inc18-Like vanA Plasmids in Michigan. Antimicrob. Agents Chemother. 52: 452-457 [Abstract] [Full Text]  
  • Ellington, M. J., Yearwood, L., Ganner, M., East, C., Kearns, A. M. (2008). Distribution of the ACME-arcA gene among methicillin-resistant Staphylococcus aureus from England and Wales. J Antimicrob Chemother 61: 73-77 [Abstract] [Full Text]  
  • Faria, N. A., Carrico, J. A., Oliveira, D. C., Ramirez, M., de Lencastre, H. (2008). Analysis of Typing Methods for Epidemiological Surveillance of both Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Strains. J. Clin. Microbiol. 46: 136-144 [Abstract] [Full Text]  
  • Tomita, T., Meehan, B., Wongkattiya, N., Malmo, J., Pullinger, G., Leigh, J., Deighton, M. (2008). Identification of Streptococcus uberis Multilocus Sequence Types Highly Associated with Mastitis. Appl. Environ. Microbiol. 74: 114-124 [Abstract] [Full Text]  
  • Witte, W., Strommenger, B., Cuny, C., Heuck, D., Nuebel, U. (2007). Methicillin-resistant Staphylococcus aureus containing the Panton-Valentine leucocidin gene in Germany in 2005 and 2006. J Antimicrob Chemother 60: 1258-1263 [Abstract] [Full Text]  
  • Donnio, P.-Y., Fevrier, F., Bifani, P., Dehem, M., Kervegant, C., Wilhelm, N., Gautier-Lerestif, A.-L., Lafforgue, N., Cormier, M., the MR-MSSA Study Group of the College de Bacterio, , Le Coustumier, A. (2007). Molecular and Epidemiological Evidence for Spread of Multiresistant Methicillin-Susceptible Staphylococcus aureus Strains in Hospitals. Antimicrob. Agents Chemother. 51: 4342-4350 [Abstract] [Full Text]  
  • Park, C., Lee, D.-G., Kim, S. W., Choi, S.-M., Park, S. H., Chun, H.-S., Choi, J.-H., Yoo, J.-H., Shin, W. S., Kang, J. H., Kim, J. H., Lee, S. Y., Kim, S. M., Pyun, B. Y. (2007). Predominance of Community-Associated Methicillin-Resistant Staphylococcus aureus Strains Carrying Staphylococcal Chromosome Cassette mec Type IVA in South Korea. J. Clin. Microbiol. 45: 4021-4026 [Abstract] [Full Text]  
  • Huang, Y.-C., Hwang, K.-P., Chen, P.-Y., Chen, C.-J., Lin, T.-Y. (2007). Prevalence of Methicillin-Resistant Staphylococcus aureus Nasal Colonization among Taiwanese Children in 2005 and 2006. J. Clin. Microbiol. 45: 3992-3995 [Abstract] [Full Text]  
  • Kim, E. S., Song, J. S., Lee, H. J., Choe, P. G., Park, K. H., Cho, J. H., Park, W. B., Kim, S.-H., Bang, J.-H., Kim, D.-M., Park, K. U., Shin, S., Lee, M. S., Choi, H. J., Kim, N. J., Kim, E.-C., Oh, M.-d., Kim, H. B., Choe, K. W. (2007). A survey of community-associated methicillin-resistant Staphylococcus aureus in Korea. J Antimicrob Chemother 60: 1108-1114 [Abstract] [Full Text]  
  • Blanc, D. S., Petignat, C., Wenger, A., Kuhn, G., Vallet, Y., Fracheboud, D., Trachsel, S., Reymond, M., Troillet, N., Siegrist, H. H., Oeuvray, S., Bes, M., Etienne, J., Bille, J., Francioli, P., Zanetti, G. (2007). Changing Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Small Geographic Area over an Eight-Year Period. J. Clin. Microbiol. 45: 3729-3736 [Abstract] [Full Text]  
  • Johnson, J. K., Arduino, S. M., Stine, O. C., Johnson, J. A., Harris, A. D. (2007). Multilocus Sequence Typing Compared to Pulsed-Field Gel Electrophoresis for Molecular Typing of Pseudomonas aeruginosa. J. Clin. Microbiol. 45: 3707-3712 [Abstract] [Full Text]  
  • Rabello, R. F., Moreira, B. M., Lopes, R. M. M., Teixeira, L. M., Riley, L. W., Castro, A. C. D. (2007). Multilocus sequence typing of Staphylococcus aureus isolates recovered from cows with mastitis in Brazilian dairy herds. J Med Microbiol 56: 1505-1511 [Abstract] [Full Text]  
  • Daskalaki, M., Otero, J. R., Sanz, F., Chaves, F. (2007). Bacteremia Due to Clonally Derived Methicillin-Resistant, Gentamicin-Susceptible Isolates and Methicillin-Susceptible, Gentamicin-Resistant Isolates of Staphylococcus aureus. J. Clin. Microbiol. 45: 3446-3448 [Abstract] [Full Text]  
  • Amorim, M. L., Faria, N. A., Oliveira, D. C., Vasconcelos, C., Cabeda, J. C., Mendes, A. C., Calado, E., Castro, A. P., Ramos, M. H., Amorim, J. M., de Lencastre, H. (2007). Changes in the Clonal Nature and Antibiotic Resistance Profiles of Methicillin-Resistant Staphylococcus aureus Isolates Associated with Spread of the EMRSA-15 Clone in a Tertiary Care Portuguese Hospital. J. Clin. Microbiol. 45: 2881-2888 [Abstract] [Full Text]  
  • Holtfreter, S., Grumann, D., Schmudde, M., Nguyen, H. T. T., Eichler, P., Strommenger, B., Kopron, K., Kolata, J., Giedrys-Kalemba, S., Steinmetz, I., Witte, W., Broker, B. M. (2007). Clonal Distribution of Superantigen Genes in Clinical Staphylococcus aureus Isolates. J. Clin. Microbiol. 45: 2669-2680 [Abstract] [Full Text]  
  • Brady, J. M., Stemper, M. E., Weigel, A., Chyou, P.-H., Reed, K. D., Shukla, S. K. (2007). Sporadic "Transitional" Community-Associated Methicillin-Resistant Staphylococcus aureus Strains from Health Care Facilities in the United States. J. Clin. Microbiol. 45: 2654-2661 [Abstract] [Full Text]  


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