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Journal of Clinical Microbiology, March 2000, p. 1247-1249, Vol. 38, No. 3
Henry M. Jackson
Foundation1 and Division of
Retrovirology, Walter Reed Army Institute of
Research,2 Rockville, Maryland 20850;
Fred Hutchinson Cancer Research Center, Seattle, Washington
981093; and Gen-Probe, Incorporated,
San Diego, California 921214
Received 24 September 1999/Returned for modification 22 November
1999/Accepted 20 December 1999
Optimal management of human immunodeficiency virus type 1 (HIV-1)
disease requires accurate quantitation of viral RNA concentrations in
plasma. Evidence for increasing geographic intermixing of HIV-1 subtypes makes equivalent quantitation of all subtypes essential. The performances of six quantitative viral RNA tests are described, for
the first time, with calibrated viral isolates of diverse subtypes.
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.
Use of Calibrated Viral Load Standards for Group M Subtypes of
Human Immunodeficiency Virus Type 1 To Assess the Performance of
Viral RNA Quantitation Tests
*
Corresponding author. Mailing address: Henry M. Jackson
Foundation, 1600 E. Gude Dr., Rockville, MD 20850. Phone: (301)
251-5042. Fax: (301) 762-7460. E-mail:
liagodzinski{at}hiv.hjf.org.
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