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Journal of Clinical Microbiology, April 2000, p. 1638-1640, Vol. 38, No. 4
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Long-Term Persistence of a Discotheque-Associated Invasive Neisseria meningitidis Group C Strain as Proven by Pulsed-Field Gel Electrophoresis and porA Gene Sequencing

Kristian Riesbeck,1,* Paula Orvelid-Mölling,2 Hans Fredlund,2 and Per Olcén2

Department of Medical Microbiology, Malmö University Hospital, Lund University, S-205 02 Malmö,1 and Department of Clinical Microbiology, Örebro Medical Centre Hospital, S-701 85 Örebro,2 Sweden

Received 12 October 1999/Accepted 27 January 2000

A cluster of a Neisseria meningitidis serogroup C strain causing invasive disease was investigated. Five out of seven cases were associated with a particular discotheque. The strains were indistinguishable, as revealed by pulsed-field gel electrophoresis and sequencing of variable regions of the porA gene, but caused strikingly different clinical presentations during 5 months.


* Corresponding author. Mailing address: Dept. of Medical Microbiology, Malmö University Hospital, Lund University, S-205 02 Malmö, Sweden. Phone: 46 40 331340. Fax: 46 40 336234. E-mail: kristian.riesbeck{at}mikrobiol.mas.lu.se.


Journal of Clinical Microbiology, April 2000, p. 1638-1640, Vol. 38, No. 4
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.



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