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Journal of Clinical Microbiology, May 2000, p. 2005-2006, Vol. 38, No. 5
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Brucella abortus Infection Acquired in Microbiology Laboratories

Pier Luigi Fiori,1,* Scilla Mastrandrea,2 Paola Rappelli,1 and Piero Cappuccinelli1

Dipartimento di Scienze Biomediche, Sezione di Microbiologia Sperimentale e Clinica,1 and Istituto di Malattie Infettive e Parassitarie,2 Università di Sassari, 07100 Sassari, Italy

Received 13 December 1999/Returned for modification 27 January 2000/Accepted 29 February 2000

We report an outbreak of laboratory-acquired Brucella abortus infection originating in the accidental breakage of a centrifuge tube. A total of 12 laboratory workers were infected (attack rate of 31%), with an incubation time ranging from 6 weeks to 5 months. Antibody titers were evaluated weekly in all personnel exposed, allowing the diagnosis of the infection in most cases before the onset of clinical symptoms, so that specific therapy could be administrated.


* Corresponding author. Mailing address: Department of Biomedical Sciences, Division of Experimental and Clinical Microbiology, University of Sassari, Viale S. Pietro 43/B, 07100 Sassari, Italy. Phone: 39 079 228299. Fax: 39 079 212345. E-mail: fioripl{at}ssmain.uniss.it.


Journal of Clinical Microbiology, May 2000, p. 2005-2006, Vol. 38, No. 5
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.



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