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Journal of Clinical Microbiology, June 2000, p. 2389-2391, Vol. 38, No. 6
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Genetic Homology among Thirteen Encephalitozoon intestinalis Isolates Obtained from Human Immunodeficiency Virus-Infected Patients with Intestinal Microsporidiosis

Olivier Liguory,1,2 Sandra Fournier,1 Claudine Sarfati,2 Francis Derouin,2 and Jean-Michel Molina1,*

Department of Infectious Diseases1 and Laboratory of Parasitology,2 Hôpital Saint-Louis, Paris, France

Received 30 December 1999/Returned for modification 26 February 2000/Accepted 25 March 2000

The ribosomal DNA internal transcribed spacer sequences of 13 unrelated Encephalitozoon intestinalis isolates obtained from human immunodeficiency virus (HIV)-infected patients with intestinal microsporidiosis were analyzed by gene amplification and DNA sequencing. Among these isolates, we found only one genetic lineage which suggests that E. intestinalis may have a clonal distribution in HIV-infected patients.

* Corresponding author. Mailing address: Clinique des Maladies Infectieuses, Hôpital Saint-Louis, 1 avenue C. Vellefaux, 75475 Paris Cedex 10, France. Phone: (33) 1 42 49 90 66. Fax: (33) 1 42 49 90 67. E-mail: molina{at}chu-stlouis.fr.

Journal of Clinical Microbiology, June 2000, p. 2389-2391, Vol. 38, No. 6
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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