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Journal of Clinical Microbiology, July 2000, p. 2753-2755, Vol. 38, No. 7
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Detection of Human Herpesvirus 6 and Varicella-Zoster Virus in Tear Fluid of Patients with Bell's Palsy by PCR

A. Pitkäranta,1,* H. Piiparinen,2 L. Mannonen,2 M. Vesaluoma,3 and A. Vaheri2

Departments of Otorhinolaryngology,1 Virology,2 and Ophthalmology,3 University of Helsinki, Helsinki, Finland

Received 13 December 1999/Returned for modification 18 February 2000/Accepted 28 April 2000

Human herpesvirus 6 DNA was detected by PCR in the tear fluid of 7 (35%) of 20 patients with Bell's palsy and of 1 (5%) of 20 healthy controls. Varicella-zoster virus was detected by PCR in the tear fluid of 2 of 20 Bell's palsy patients but in none of the tear fluids from 20 healthy controls. These findings suggest an association between human herpesviruses and Bell's palsy.

* Corresponding author. Mailing address: Department of Otorhinolaryngology, University of Helsinki, PL 220, 00029 HYKS, Finland. Phone: 358-9-47173697. Fax: 358-9-47175010. E-mail: anne.pitkaranta{at}helsinki.fi.

Journal of Clinical Microbiology, July 2000, p. 2753-2755, Vol. 38, No. 7
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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