This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Chan, P. K. S.
Right arrow Articles by Cheng, A. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chan, P. K. S.
Right arrow Articles by Cheng, A. F.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, July 2000, p. 2772-2773, Vol. 38, No. 7
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Survey for the Presence and Distribution of Human Herpesvirus 8 in Healthy Brain

Paul K. S. Chan,1,* Ho-Keung Ng,2 Jo L. K. Cheung,1 and Augustine F. Cheng1

Department of Microbiology1 and Department of Anatomical and Cellular Pathology,2 The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China

Received 6 March 2000/Returned for modification 27 March 2000/Accepted 28 April 2000

Brain tissues from both sides of the cerebellum and frontal, temporal, parietal, and occipital lobes were collected postmortem from 30 patients for human herpesvirus 8 (HHV-8) detection by PCR. Overall, 42 of 300 (14.0%) samples were positive, with similar rates for each position. Nineteen patients (63.3%) were positive and showed a significant increase in positivity with age (P = 0.007). The results indicate a neuroinvasive and neuropersistent potential of HHV-8.

* Corresponding author. Mailing address: Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China. Phone: (852) 2632-3333. Fax: (852) 2647-3227. E-mail: paulkschan{at}cuhk.edu.hk.

Journal of Clinical Microbiology, July 2000, p. 2772-2773, Vol. 38, No. 7
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Caselli, E., Galvan, M., Santoni, F., Rotola, A., Caruso, A., Cassai, E., Luca, D. D. (2003). Human herpesvirus-8 (Kaposi's sarcoma-associated virus) ORF50 increases in vitro cell susceptibility to human immunodeficiency virus type 1 infection. J. Gen. Virol. 84: 1123-1131 [Abstract] [Full Text]  
  • Terry, L. A., Stewart, J. P., Nash, A. A., Fazakerley, J. K. (2000). Murine gammaherpesvirus-68 infection of and persistence in the central nervous system. J. Gen. Virol. 81: 2635-2643 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»