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Journal of Clinical Microbiology, August 2000, p. 3087-3091, Vol. 38, No. 8
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Borna Disease in a Free-Ranging Lynx (Lynx lynx)

M.-P. Degiorgis,1 A.-L. Berg,2 C. Hård af Segerstad,1 T. Mörner,1 M. Johansson,2 and M. Berg3,*

Department of Wildlife, National Veterinary Institute,1 and Department of Pathology2 and Department of Veterinary Microbiology, Section of Immunology,3 Swedish University of Agricultural Sciences, Uppsala, Sweden

Received 3 February 2000/Returned for modification 5 May 2000/Accepted 11 May 2000

A free-ranging lynx (Lynx lynx) was shot because of its abnormal behavior. Histopathological examination revealed a nonsuppurative meningoencephalitis. In situ hybridization, immunohistochemistry, and reverse transcriptase PCR analysis showed the presence of Borna disease virus infection in the brain. To our knowledge, this is the first confirmed case of Borna disease in a large felid.

* Corresponding author. Mailing address: Department of Veterinary Microbiology, Section of Immunology, Swedish University of Agricultural Sciences, Dag Hammarskjöldsv-Husargatan, Box 588, BMC, 751 23 Uppsala, Sweden. Phone: 46-18-471 41 72. Fax: 46-18-471 43 82. E-mail: Mikael.Berg{at}vmm.slu.se.

Journal of Clinical Microbiology, August 2000, p. 3087-3091, Vol. 38, No. 8
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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