This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Nakagawa, N.
Right arrow Articles by Okuno, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nakagawa, N.
Right arrow Articles by Okuno, Y.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, September 2000, p. 3467-3469, Vol. 38, No. 9
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Heterogeneity of Influenza B Virus Strains in One Epidemic Season Differentiated by Monoclonal Antibodies and Nucleotide Sequences

Naoko Nakagawa,1,* Ritsuko Kubota,2 Akiko Maeda,2 Toshimasa Nakagawa,3 and Yoshinobu Okuno2

Division of Bacteriology1 and Division of Virology,2 Department of Public Health, Osaka Prefectural Institute of Public Health, Nakamichi, Higashinari-ku, Osaka 537-0025, and Department of Clinical Pathology, Osaka Medical College, Takatsuki 569-8686,3 Japan

Received 2 December 1999/Returned for modification 28 April 2000/Accepted 12 June 2000

Seventy-three B/Victoria group strains isolated in the 1996-1997 influenza season were divided into three groups according to the degree of reactivity to monoclonal antibody 8E6. Analysis of nucleotide sequences of the HA1 region clarified that single amino acid substitutions were responsible for the difference in reactivity to 8E6.

* Corresponding author. Mailing address: Division of Bacteriology, Department of Public Health, Osaka Prefectural Institute of Public Health, 3-69, 1-Chome, Nakamichi, Higashinari-ku, Osaka, 537-0025, Japan. Phone: 81-6-6972-1321. Fax: 81-6-6972-0772. E-mail: nakagawa{at}iph.pref.osaka.jp.

Journal of Clinical Microbiology, September 2000, p. 3467-3469, Vol. 38, No. 9
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Nakagawa, N., Higashi, N., Nakagawa, T. (2009). Cocirculation of Antigenic Variants and the Vaccine-Type Virus during the 2004-2005 Influenza B Virus Epidemics in Japan. J. Clin. Microbiol. 47: 352-357 [Abstract] [Full Text]  
  • Wang, Q., Cheng, F., Lu, M., Tian, X., Ma, J. (2008). Crystal Structure of Unliganded Influenza B Virus Hemagglutinin. J. Virol. 82: 3011-3020 [Abstract] [Full Text]  
  • Wang, Q., Tian, X., Chen, X., Ma, J. (2007). Structural basis for receptor specificity of influenza B virus hemagglutinin. Proc. Natl. Acad. Sci. USA 104: 16874-16879 [Abstract] [Full Text]  
  • Nakagawa, N., Suzuoki, J., Kubota, R., Kobatake, S., Okuno, Y. (2006). Discovery of the Neutralizing Epitope Common to Influenza B Virus Victoria Group Isolates in Japan. J. Clin. Microbiol. 44: 1564-1566 [Abstract] [Full Text]  
  • Nakagawa, N., Kubota, R., Okuno, Y. (2005). Variation of the Conserved Neutralizing Epitope in Influenza B Virus Victoria Group Isolates in Japan. J. Clin. Microbiol. 43: 4212-4214 [Abstract] [Full Text]  
  • Nakagawa, N., Kubota, R., Maeda, A., Okuno, Y. (2004). Influenza B Virus Victoria Group with a New Glycosylation Site Was Epidemic in Japan in the 2002-2003 Season. J. Clin. Microbiol. 42: 3295-3297 [Abstract] [Full Text]  
  • Chi, X. S., Bolar, T. V., Zhao, P., Rappaport, R., Cheng, S.-M. (2003). Cocirculation and Evolution of Two Lineages of Influenza B Viruses in Europe and Israel in the 2001-2002 Season. J. Clin. Microbiol. 41: 5770-5773 [Abstract] [Full Text]  
  • Nakagawa, N., Kubota, R., Nakagawa, T., Okuno, Y. (2003). Neutralizing epitopes specific for influenza B virus Yamagata group strains are in the 'loop'. J. Gen. Virol. 84: 769-773 [Abstract] [Full Text]  
  • Nakagawa, N., Nukuzuma, S., Haratome, S., Go, S., Nakagawa, T., Hayashi, K. (2002). Emergence of an Influenza B Virus with Antigenic Change. J. Clin. Microbiol. 40: 3068-3070 [Abstract] [Full Text]  
  • Nakagawa, N., Kubota, R., Nakagawa, T., Okuno, Y. (2001). Antigenic variants with amino acid deletions clarify a neutralizing epitope specific for influenza B virus Victoria group strains. J. Gen. Virol. 82: 2169-2172 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»