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Journal of Clinical Microbiology, September 2000, p. 3489-3491, Vol. 38, No. 9
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Characterization of Neisseria gonorrhoeae Strains with Decreased Susceptibility to Fluoroquinolones Isolated in Greece from 1996 to 1999

Angeliki Mavroidi,1 Leonidas S. Tzouvelekis,2 Panayotis T. Tassios,2 Alexandros Flemetakis,3 Maria Daniilidou,4 and Eva Tzelepi1,*

National Reference Center for Neisseria gonorrhoeae, Department of Bacteriology, Hellenic Pasteur Institute,1 Laboratory of Antimicrobial Agents, Department of Microbiology, Athens University Medical School,2 and Microbiology Laboratory of the "Andreas Sygros" Hospital for Skin and Venereal Diseases,3 Athens, and Microbiology Laboratory of the Venereal Hospital of Thessaloniki, Thessaloniki,4 Greece

Received 13 April 2000/Returned for modification 29 May 2000/Accepted 22 June 2000

Of the 331 Neisseria gonorrhoeae strains isolated in Greece from 1996 to 1999, 39 (11.8%) exhibited decreased susceptibility to quinolones due to gyrA and parC mutations. Conventional typing and pulsed-field gel electrophoresis showed that 34 of these isolates were clonally related. Epidemiological data indicated that the epidemic clone was sustained in a group of high-frequency transmitters.

* Corresponding author. Mailing address: Department of Bacteriology, Hellenic Pasteur Institute, 127 Vass. Sofias Ave., 11521-Athens, Greece. Phone: 30 (1) 6478810. Fax: 30 (1) 6423498. E-mail: tzelepi{at}otenet.gr.

Journal of Clinical Microbiology, September 2000, p. 3489-3491, Vol. 38, No. 9
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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