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Journal of Clinical Microbiology, January 2001, p. 375-376, Vol. 39, No. 1
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.1.375-376.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Investigation of Optimal Specimen Type and Sampling Time for Detection of Measles Virus RNA during a Measles Epidemic

Michaela A. Riddell,* Doris Chibo, Heath A. Kelly, Michael G. Catton, and Christopher J. Birch

Victorian Infectious Diseases Reference Laboratory, North Melbourne, Victoria, Australia

Received 13 July 2000/Returned for modification 13 September 2000/Accepted 23 October 2000

At various times postonset of rash, 74 patients positive for measles virus-specific immunoglobulin M provided samples for detection of measles virus RNA by a reverse transcriptase PCR. Of lymphocytes, urine, throat swab, and serum specimens, throat swab specimens were optimal for detection of measles virus RNA during the first 2 weeks after the rash.

* Corresponding author. Mailing address: Epidemiology and Public Health Division, Victorian Infectious Diseases Reference Laboratory, 10 Wreckyn St., North Melbourne 3051, Victoria, Australia. Phone: 61 3 9342 2686. Fax: 61 3 9342 2665. E-mail: michaela.riddell{at}mh.org.au.

Journal of Clinical Microbiology, January 2001, p. 375-376, Vol. 39, No. 1
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.1.375-376.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 2001 by the American Society for Microbiology. All rights reserved.