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Journal of Clinical Microbiology, November 2001, p. 4152-4154, Vol. 39, No. 11
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.11.4152-4154;2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Epstein-Barr Virus (EBV) DNA in Sera of Patients with Primary EBV Infection

K. H. Chan,1,* M. H. Ng,2 W. H. Seto,1 and J. S. M. Peiris2

Department of Microbiology, Queen Mary Hospital,1 and Department of Microbiology, The University of Hong Kong,2 Hong Kong, Special Administrative Region, People's Republic of China

Received 24 May 2001/Returned for modification 30 July 2001/Accepted 13 August 2001

Detection of Epstein-Barr Virus (EBV) DNA by PCR in serum had a sensitivity of 80%, a specificity of 94%, and positive and negative predictive values of 95 and 79%, respectively, for the diagnosis of primary EBV infection. We suggest that this is a useful addition to the panel of tests used for this purpose.

* Corresponding author. Mailing address: Department of Microbiology, University Pathology Building, Queen Mary Hospital Compound, Pokfulam, Hong Kong. Phone: (852) 2855 4888. Fax: (852) 2855 1241. E-mail: chan.kwok.hung{at}hkucc.hku.hk.

Journal of Clinical Microbiology, November 2001, p. 4152-4154, Vol. 39, No. 11
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.11.4152-4154;2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 2001 by the American Society for Microbiology. All rights reserved.