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Journal of Clinical Microbiology, November 2001, p. 4190-4192, Vol. 39, No. 11
0095-1137/01/$04.00+0 DOI: 10.1128/JCM.39.11.4190-4192.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.
Determining Confidence Intervals When Measuring Genetic Diversity
and the Discriminatory Abilities of Typing Methods for
Microorganisms
Hajo
Grundmann,1,*
Satoshi
Hori,1 and
Gregor
Tanner2
Division of Microbiology and Infectious
Diseases, University Hospital Nottingham,1 and
School of Mathematical Sciences,2
University of Nottingham, Nottingham NG7 2UH, United Kingdom
Received 21 June 2001/Returned for modification 24 July
2001/Accepted 21 August 2001
We describe here a method for determining confidence intervals for
a commonly used index of diversity. This approach facilitates the
comparison of the genetic population structure of microorganisms isolated from different environments and improves the objective assessment of the discriminatory power of typing techniques.
*
Corresponding author. Mailing address: Division of
Microbiology and Infectious Diseases, University Hospital, Queen's
Medical Centre, Clifton Blvd., Nottingham NG7 2UH, United Kingdom.
Phone: 44-115-970-9162. Fax: 44-115-970-9233. E-mail:
Hajo.Grundmann{at}Nottingham.ac.uk.
Journal of Clinical Microbiology, November 2001, p. 4190-4192, Vol. 39, No. 11
0095-1137/01/$04.00+0 DOI: 10.1128/JCM.39.11.4190-4192.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.
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