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Journal of Clinical Microbiology, December 2001, p. 4591-4592, Vol. 39, No. 12
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.12.4591-4592.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

First European Pediatric Case of Human Granulocytic Ehrlichiosis

Maja Arnez,1,* Miroslav Petrovec,2 Stanka Lotric-Furlan,1 Tatjana Avsic Zupanc,2 and Franc Strle1

Department of Infectious Diseases, University Medical Center Ljubljana, Japljeva 2, 1525 Ljubljana,1 and Institute of Microbiology and Immunology, Medical Faculty, University of Ljubljana, Zaloska 4, 1000 Ljubljana,2 Slovenia

Received 21 June 2001/Returned for modification 26 August 2001/Accepted 5 October 2001

Herein we report on the first confirmed pediatric case of acute human granulocytic ehrlichiosis in Europe. Presentation in this 11-year-old girl was comparable to clinical findings seen in adult European patients with human granulocytic ehrlichiosis; i.e., she had self-limited febrile illness with leukopenia, thrombocytopenia, and elevated serum C-reactive protein concentration. It is of interest that the patient not only had a fourfold change in antibody titer to Ehrlichia phagocytophila but also developed antibodies to Ehrlichia chaffeensis and that her PCR test result was positive on the third as well as on the 22nd day after the onset of illness, that is, 16 days after spontaneous defervescence.

* Corresponding author. Mailing address: Department of Infectious Diseases, University Medical Center, Japljeva 2, 1525 Ljubljana, Slovenia. Phone: 386 1 2310 558. Fax: 386 1 2302 781. E-mail: maja.arnez{at}kclj.si.

Journal of Clinical Microbiology, December 2001, p. 4591-4592, Vol. 39, No. 12
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.12.4591-4592.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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