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Journal of Clinical Microbiology, February 2001, p. 730-732, Vol. 39, No. 2
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.2.730-732.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Evaluation of a Rapid Optical Immunoassay for Influenza Viruses (FLU OIA Test) in Comparison with Cell Culture and Reverse Transcription-PCR

Guy Boivin,1,* Isabelle Hardy,1 and Andrew Kress2

Research Center in Infectious Diseases of the Centre Hospitalier Universitaire de Québec and Laval University, Québec City, Quebec, Canada,1 and Surveillance Data, Inc., Philadelphia, Pennsylvania2

Received 13 July 2000/Returned for modification 8 September 2000/Accepted 8 November 2000

The FLU OIA test was evaluated with 146 throat swab specimens from subjects with a flu-like illness in six Canadian clinics during the 1999-2000 flu season. The rate of positivity of the FLU OIA test (41.5%) was significantly lower than that of cell culture (55.2%) or reverse transcription-PCR (55.9%) during a season in which only influenza A virus was detected.

* Corresponding author. Mailing address: CHUQ, pavillon CHUL, room RC-709, 2705 blvd. Laurier, Sainte-Foy, Québec, Canada GIV 4G2. Phone: (418) 654-2705. Fax: (418) 654-2715. E-mail: Guy.Boivin{at}crchul.ulaval.ca.

Journal of Clinical Microbiology, February 2001, p. 730-732, Vol. 39, No. 2
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.2.730-732.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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