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Journal of Clinical Microbiology, March 2001, p. 1121-1123, Vol. 39, No. 3
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.3.1121-1123.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Multisite Comparison of Reproducibility and Recovery from the Standard and Ultrasensitive Roche AMPLICOR HIV-1 MONITOR Assays

Donald J. Brambilla,1,* Suzanne Granger,1 Cheryl Jennings,2 and James W. Bremer2

New England Research Institutes, Inc., Watertown, Massachusetts 02472,1 and Rush Medical College, Chicago, Illinois 606122

Received 9 May 2000/Returned for modification 23 October 2000/Accepted 15 December 2000

Reproducibility and recovery from the standard and ultrasensitive Roche AMPLICOR HIV-1 MONITOR kits were compared in 19 laboratories. The results were generally similar, but the consistently low level of recovery from the ultrasensitive assay in one laboratory points to the need to include external controls in order to track assay performance.

* Corresponding author. Mailing address: New England Research Institutes, 9 Galen St., Watertown, MA 02472. Phone: (617) 923-7747, ext. 230. Fax: (617) 926-1142. E-mail: donb{at}neri.org.

Journal of Clinical Microbiology, March 2001, p. 1121-1123, Vol. 39, No. 3
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.3.1121-1123.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Salimnia, H., Moore, E. C., Crane, L. R., MacArthur, R. D., Fairfax, M. R. (2005). Discordance between Viral Loads Determined by Roche COBAS AMPLICOR Human Immunodeficiency Virus Type 1 Monitor (Version 1.5) Standard and Ultrasensitive Assays Caused by Freezing Patient Plasma in Centrifuged Becton-Dickinson Vacutainer Brand Plasma Preparation Tubes. J. Clin. Microbiol. 43: 4635-4639 [Abstract] [Full Text]  
  • Jennings, C., Brambilla, D. J., Bremer, J. W. (2002). Ratio of Two Successive Optical Densities from the Roche HIV-1 Monitor Test as a Measure of Accuracy of Estimates of Human Immunodeficiency Virus RNA Concentration. J. Clin. Microbiol. 40: 1067-1068 [Abstract] [Full Text]  


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