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Journal of Clinical Microbiology, March 2001, p. 1137-1139, Vol. 39, No. 3
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.3.1137-1139.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Heterogeneity of Pneumocystis Sterol Profiles of Samples from Different Sites in the Same Pair of Lungs Suggests Coinfection by Distinct Organism Populations

Zunika Amit and Edna S. Kaneshiro*

Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio 45221

Received 17 July 2000/Returned for modification 12 October 2000/Accepted 12 December 2000

Sterol profiles of samples taken from different sites of a Pneumocystis-infected human lung showed large variations in pneumocysterol similar to those that occur among samples from different patients. Thus, the influence of diet or drugs on pneumocysterol accumulation was ruled out, suggesting distinct phenotypic populations as the basis for the heterogeneity.

* Corresponding author. Mailing address: Department of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221-0006. Phone: (513) 556-9712. Fax: (513) 556-5280. E-mail: Edna.Kaneshiro{at}uc.edu.

Journal of Clinical Microbiology, March 2001, p. 1137-1139, Vol. 39, No. 3
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.3.1137-1139.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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