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Journal of Clinical Microbiology, March 2001, p. 1204-1206, Vol. 39, No. 3
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.3.1204-1206.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Molecular Evidence of Male-to-Female Sexual Transmission of Hepatitis C Virus after Vaginal and Anal Intercourse

Philippe Halfon,1,* Hervé Riflet,2 Christophe Renou,3 Yves Quentin,4 and Patrice Cacoub5

Département de Virologie, Laboratoire Alphabio,1 and Laboratoire de Chimie Biologie, CNRS,3 Marseille, Département d'hépato-Gastroenterologie, CH Ajaccio,2 Département d'hépato-Gastroenterologie, CH-Hyères,4 and Département de Médecine Interne Hôpital La Pitié-Salpétrière, Paris,5 France

Received 27 July 2000/Returned for modification 22 September 2000/Accepted 19 December 2000

Hepatitis C virus (HCV) was transmitted from a chronic carrier to his female partner during unprotected anal and vaginal intercourse. Based on HVR1 and phylogenetic tree analysis, the couple had closely related isolates. These findings confirm sexual transmission of HCV without other risk factors.

* Corresponding author. Mailing address: Département de Virologie, Laboratoire Alphabio, 23 Rue de Friedland, Hôpital Ambroise Paré, 13006 Marseille, France. Phone: (33) 4 91 25 41 00. Fax: (33) 4 91 79 20 44. E-mail address: philippe.halfon{at}alphabio.fr.

Journal of Clinical Microbiology, March 2001, p. 1204-1206, Vol. 39, No. 3
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.3.1204-1206.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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