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Journal of Clinical Microbiology, May 2001, p. 1710-1715, Vol. 39, No. 5
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.5.1710-1715.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Genetic Diversity of Neisseria lactamica Strains from Epidemiologically Defined Carriers

Dirk Alber, Mark Oberkötter, Sebastian Suerbaum, Heike Claus, Matthias Frosch, and Ulrich Vogel*

Institut für Hygiene und Mikrobiologie, Universität Würzburg, Würzburg, Germany

Received 13 November 2000/Returned for modification 3 February 2001/Accepted 17 February 2001

We assessed the genetic diversity of 26 Neisseria lactamica strains from epidemiologically related sources, i.e., groups of kindergartens and primary schools in three Bavarian towns, by the partial sequencing of the argF, rho, recA, and 16S ribosomal genes. We found a total of 17 genotypes, of which 12 were found only in one strain. The genotypes comprised 5 alleles of the argF gene, 9 of rho, 8 of recA, and 10 of the 16S ribosomal DNA. Sequence analysis by determination of homoplasy ratios and split decomposition analysis revealed abundant recombination within N. lactamica.

* Corresponding author. Mailing address: Institut für Hygiene und Mikrobiologie, Universität Würzburg, Josef-Schneider-Str. 2, 97080 Würzburg, Germany. Phone: 49(931)201 3802. Fax: 49(931)201 3445. E-mail: uvogel{at}hygiene.uni-wuerzburg.de.

Journal of Clinical Microbiology, May 2001, p. 1710-1715, Vol. 39, No. 5
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.5.1710-1715.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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Copyright © 2001 by the American Society for Microbiology. All rights reserved.