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Journal of Clinical Microbiology, June 2001, p. 2313-2316, Vol. 39, No. 6
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.6.2313-2316.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Genotypic Diversity of Mutans Streptococci in Brazilian Nursery Children Suggests Horizontal Transmission

Renata O. Mattos-Graner,1 Yihong Li,2 Page W. Caufield,2 Margaret Duncan,3 and Daniel J. Smith1,*

Departments of Immunology1 and Molecular Genetics,3 The Forsyth Institute, Boston, Massachusetts, and Department of Oral Biology, School of Dentistry, University of Alabama, Birmingham, Alabama2

Received 5 March 2001/Accepted 31 March 2001

Streptococcus mutans strains were isolated from cohorts of Brazilian nursery school children and genotyped by arbitrarily primed PCR and restriction fragment length polymorphism analysis. Of 24 children with two to five S. mutans isolates, 29% carried two or more genotypes. The presence of matching genotypes of S. mutans among children attending one nursery suggests horizontal transmission.

* Corresponding author. Mailing address: Department of Immunology, The Forsyth Institute, 140 The Fenway, Boston, MA 02115. Phone: (617) 262-5200, ext. 309. Fax: (617) 262-4021. E-mail: dsmith{at}forsyth.org.

Journal of Clinical Microbiology, June 2001, p. 2313-2316, Vol. 39, No. 6
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.6.2313-2316.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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Copyright © 2001 by the American Society for Microbiology. All rights reserved.