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Journal of Clinical Microbiology, July 2001, p. 2640-2641, Vol. 39, No. 7
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.7.2640-2641.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Rapid Diagnosis of Histoplasma capsulatum Endocarditis Using the AccuProbe on an Excised Valve

Roy F. Chemaly,1,2 J. Walton Tomford,2 Gerri S. Hall,1 Mary Sholtis,1 Jimmy D. Chua,1 and Gary W. Procop1,*

Department of Clinical Pathology, Section of Clinical Microbiology,1 and Department of Infectious Diseases,2 The Cleveland Clinic Foundation, Cleveland, Ohio

Received 6 February 2001/Returned for modification 7 March 2001/Accepted 24 April 2001

Histoplasma capsulatum is an infrequent but serious cause of endocarditis. The definitive diagnosis requires culture, which may require a long incubation. We demonstrated the ability of the Histoplasma capsulatum AccuProbe to accurately identify this organism when applied directly on an excised valve that contained abundant yeast forms consistent with H. capsulatum.

* Corresponding author. Mailing address: Department of Clinical Pathology, Section of Microbiology, The Cleveland Clinic Foundation, 9500 Euclid Ave./L 40, Cleveland, OH 44195. Phone: (216) 444-5879. Fax: (216) 445-6985. E-mail: procopg{at}ccf.org.

Journal of Clinical Microbiology, July 2001, p. 2640-2641, Vol. 39, No. 7
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.7.2640-2641.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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  • Mahesh, B., Angelini, G., Caputo, M., Jin, X. Y., Bryan, A. (2005). Prosthetic Valve Endocarditis. Ann. Thorac. Surg. 80: 1151-1158 [Abstract] [Full Text]  
  • Martagon-Villamil, J., Shrestha, N., Sholtis, M., Isada, C. M., Hall, G. S., Bryne, T., Lodge, B. A., Reller, L. B., Procop, G. W. (2003). Identification of Histoplasmacapsulatum from Culture Extracts by Real-Time PCR. J. Clin. Microbiol. 41: 1295-1298 [Abstract] [Full Text]  


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