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Journal of Clinical Microbiology, August 2001, p. 2961-2963, Vol. 39, No. 8
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.8.2961-2963.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Correlation between Genotype and Phenotypic Categorization of Staphylococci Based on Methicillin Susceptibility and Resistance

Elizabeth Gradelski, Lourdes Valera, Lauren Aleksunes, Daniel Bonner, and Joan Fung-Tomc*

Department of Microbiology, Bristol-Myers Squibb Company, Wallingford, Connecticut 06492

Received 12 March 2001/Returned for modification 26 April 2001/Accepted 17 May 2001

Positive correlation between methicillin and oxacillin susceptibility test results and the detection of the mecA gene was observed for Staphylococcus aureus, S. epidermidis, and S. haemolyticus as well as among mecA+ strains of other species of coagulase-negative staphylococci (CNS). However, at least 50% of the mecA-negative strains of these other species of CNS were falsely classified as methicillin and oxacillin resistant.

* Corresponding author. Mailing address: Bristol-Myers Squibb Company, Department of Microbiology---104, 5 Research Parkway, Wallingford, CT 06492. Phone: (203) 677-6370. Fax: (203) 677-6771. E-mail: fungtomj{at}bms.com.

Journal of Clinical Microbiology, August 2001, p. 2961-2963, Vol. 39, No. 8
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.8.2961-2963.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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