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Journal of Clinical Microbiology, August 2001, p. 2999-3001, Vol. 39, No. 8
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.8.2999-3001.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Serological Differentiation of Experimentally Induced Candida dubliniensis and Candida albicans Infections

María D. Moragues,1 Miren J. Omaetxebarria,2 Natalia Elguezabal,2 Joseba Bikandi,2 Guillermo Quindós,2 David C. Coleman,3 and José Pontón2,*

Departamento de Enfermería I1 and Departamento de Inmunología, Microbiología y Parasitología,2 Facultad de Medicina y Odontología, Universidad del País Vasco, E-48080 Bilbao, Vizcaya, Spain, and Microbiology Research Unit, Department of Oral Surgery and Oral Pathology, School of Dental Science, Trinity College, University of Dublin, Dublin 2, Republic of Ireland3

Received 2 April 2001/Returned for modification 2 May 2001/Accepted 3 June 2001

Using a rabbit model of systemic infection, we show that it is possible to differentiate infections caused by Candida dubliniensis and other Candida species by detecting the antibody response mounted by the infected animals. These results confirm our previous observation in a patient with C. dubliniensis candidemia and suggest that detection of C. dubliniensis-specific antibodies is useful in the diagnosis of invasive candidiasis caused by this yeast.

* Corresponding author. Mailing address: Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Odontología, Universidad del País Vasco, Apartado 699, E-48080 Bilbao, Vizcaya, Spain. Phone: 34-94-601-2855. Fax: 34-94-464-9266. E-mail: oipposaj{at}lg.ehu.es.

Journal of Clinical Microbiology, August 2001, p. 2999-3001, Vol. 39, No. 8
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.8.2999-3001.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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Copyright © 2001 by the American Society for Microbiology. All rights reserved.