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J Clin Microbiol. 1976 July; 4(1): 106-107
Copyright © 1976 American Society for Microbiology. All Rights Reserved.

Recovery of Applied Human Leukocyte Interferon from the Nasal Mucosa of Chimpanzees and Humans

Paul E. Johnson*, Stephen B. Greenberg, Maurice W. Harmon, Bobby R. Alford and Robert B. Couch

* Department of Otorhinolaryngology and Communicative Sciences, Baylor College of Medicine, Houston, Texas 77030
Department of Microbiology and Immunology, Baylor College of Medicine, Houston, Texas 77030

ABSTRACT

Intranasally applied human leukocyte interferon was recovered locally in 9 of 10 chimpanzees and 3 of 3 human volunteers tested. A 5- to 50-fold reduction in interferon was observed over 60 min.

J Clin Microbiol. 1976 July; 4(1): 106-107
Copyright © 1976 American Society for Microbiology. All Rights Reserved.





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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 1976 by the American Society for Microbiology. All rights reserved.