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J Clin Microbiol. 1976 September; 4(3): 306-308
Copyright © 1976 American Society for Microbiology. All Rights Reserved.

Immune Response to Acute Otitis Media: Association Between Middle Ear Fluid Antibody and the Clearing of Clinical Infection

^* Huntsville Hospital, Huntsville, Alabama 35801
Departments of Microbiology and Immunology, SUNY, Downstate Medical Center, Brooklyn, New York 11203
Departments of Pediatrics and Microbiology, University Medical Center, Birmingham, Alabama 35294

ABSTRACT

Clearing of the middle ear fluid in patients with acute otitis media due to Streptococcus pneumoniae or Haemophilus influenzae was significantly associated with the presence and concentration of specific antibody in the middle ear fluid at the time of diagnosis.

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