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Journal of Clinical Microbiology, January 2002, p. 275-277, Vol. 40, No. 1
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.1.275-277.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Population-Based Survey of Antimicrobial Susceptibility and Serotype Distribution of Streptococcus pneumoniae from Meningitis Patients in Salvador, Brazil

Joice Neves Reis,1,2 Soraia Machado Cordeiro,1 Steven J. Coppola,3 Kátia Salgado,4 Maria G. S. Carvalho,5 Lúcia M. Teixeira,5 Terry A. Thompson,6 Richard R. Facklam,6 Mitermayer G. Reis,1 and Albert I. Ko1,3*

Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde,1 Faculdade de Farmácia, Universidade Federal da Bahia,2 Division of International Medicine and Infectious Diseases, Department of Medicine, Weill Medical College of Cornell University, New York, New York 10021,3 Hospital Couto Maia, Secretaria da Saúde do Estado da Bahia, Salvador,4 Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil,5 Streptococcus Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia 303336

Received 11 June 2001/ Returned for modification 10 August 2001/ Accepted 9 October 2001

Penicillin-nonsusceptible strains were isolated from 15% of 303 individuals with pneumococcal meningitis identified during a 4-year surveillance study in Salvador, Brazil. The estimated rate of coverage of the seven-valent conjugate vaccine was 74% among patients <5 years of age and 94% among those infected with nonsusceptible isolates, indicating that the use of conjugate vaccines may be an approach to the control of emerging penicillin resistance in Brazil.

* Corresponding author. Mailing address: Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz/MS, Rua Waldemar Falcão, 121, Salvador, Bahia 40295-001, Brazil. Phone: (55-71) 356-4320. Fax: (55-71) 356-2155. E-mail: aik2001{at}med.cornell.edu.

Journal of Clinical Microbiology, January 2002, p. 275-277, Vol. 40, No. 1
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.1.275-277.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 2002 by the American Society for Microbiology. All rights reserved.