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Journal of Clinical Microbiology, January 2002, p. 306-308, Vol. 40, No. 1
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.1.306-308.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Diagnosis of Placental Malaria

Frank P. Mockenhaupt,1* Ulrike Ulmen,1 Christiane von Gaertner,2 George Bedu-Addo,3 and Ulrich Bienzle1

Institute of Tropical Medicine, Charité, Humboldt University, Berlin, Germany,1 Presbyterian Mission Hospital, Agogo, Asante Akim,2 Komfo Anoyke Teaching Hospital, School of Medical Sciences, University of Science and Technology, Kumasi, Ghana3

Received 2 August 2001/ Returned for modification 17 September 2001/ Accepted 28 October 2001

In a group of 596 delivering Ghanaian women, the sensitivities of peripheral blood thick film microscopy, ICT Malaria P.f/P.v test, and PCR in detecting microscopically confirmed placental Plasmodium falciparum infection were 42, 80, and 97%, respectively. In addition to the gross underestimation of placental malaria by peripheral blood film microscopy, submicroscopic infections were found to be a risk factor for maternal anemia.

* Corresponding author. Mailing address: Institut für Tropenmedizin, Spandauer Damm 130, 14050 Berlin, Germany. Phone: 49 30 30116 750. Fax: 49 30 30116 888. E-mail: frank.mockenhaupt{at}charite.de.

Journal of Clinical Microbiology, January 2002, p. 306-308, Vol. 40, No. 1
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.1.306-308.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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