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Journal of Clinical Microbiology, October 2002, p. 3831-3834, Vol. 40, No. 10
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.10.3831-3834.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Erythromycin-Resistant Group A Streptococcal Isolates Recovered in Sofia, Bulgaria, from 1995 to 2001

Antoaneta Detcheva,1* Richard R. Facklam,2 and Bernard Beall2

National Center of Infectious and Parasitic Diseases, Sofia 1504, Bulgaria,1 World Health Organization Collaborating Center for Streptococci, Centers for Disease Control and Prevention, Atlanta, Georgia 303332

Received 31 May 2002/ Returned for modification 1 July 2002/ Accepted 15 July 2002

The frequency of erythromycin resistance within group A streptococci in Sofia, Bulgaria, from 1995 to 2001 was 2.1% (26 isolates). Of this, 57.7% was macrolide-lincosamide-streptogramin (MLS) inducible, 7.7% was MLS constitutive, and 34.6% had the M phenotype. Eleven different emm sequence types were found among 25 erythromycin-resistant isolates tested. Nineteen of 26 erythromycin-resistant isolates were additionally resistant to tetracycline and/or chloramphenicol.

* Corresponding author. Mailing address: National Center of Infectious and Parasitic Diseases, 26 Yanko Sakazov Blvd., Sofia 1504, Bulgaria. Phone: 359 2 9446999-314. Fax: 359 2 9433075. E-mail: Detcheva{at}hotmail.com.

Journal of Clinical Microbiology, October 2002, p. 3831-3834, Vol. 40, No. 10
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.10.3831-3834.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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