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Journal of Clinical Microbiology, October 2002, p. 3874-3876, Vol. 40, No. 10
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.10.3874-3876.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Japanese Spotted Fever Involving the Central Nervous System: Two Case Reports and a Literature Review

Manabu Araki,^1, Katsuya Takatsuka,¹ Junichiro Kawamura,^1* and Yuko Kanno²

Neurology,¹ Dermatology, Kobe City General Hospital, Hyogo, Japan²

Received 15 March 2002/ Accepted 17 July 2002

ABSTRACT

Japanese spotted fever (JSF), first reported in 1984, is a rickettsial disease caused by Rickettsia japonica. Until now, affliction of the central nervous system has been rarely reported. Here we report two cases of JSF associated with a central nervous system disorder such as meningoencephalitis.

FOOTNOTES

Present address: Department of Immunology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo 187-8502, Japan.

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