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Journal of Clinical Microbiology, December 2002, p. 4670-4674, Vol. 40, No. 12
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.12.4670-4674.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Bartonella henselae and Bartonella elizabethae as Potential Canine Pathogens

Angela M. Mexas, Susan I. Hancock, and Edward B. Breitschwerdt*

Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina

Received 27 March 2002/ Returned for modification 23 July 2002/ Accepted 30 August 2002

Bartonella henselae or Bartonella elizabethae DNA from EDTA-anticoagulated blood samples obtained from four dogs was amplified and sequenced. The results showed that B. elizabethae should be added to the list of Bartonella species (i.e., B. vinsonii subsp. berkhoffii, B. henselae, and B. clarridgeiae) that are currently recognized as infectious agents in dogs. Furthermore, these results may have potential zoonotic implications, particularly if dogs can serve as a previously unrecognized reservoir for B. henselae. Although the clinical relevance of these observations remains to be determined, it is possible that molecular diagnostic techniques such as PCR may help to implicate a spectrum of Bartonella spp. as a cause of or a cofactor in chronic canine and human diseases of poorly defined causation.

* Corresponding author. Mailing address: Department of Clinical Sciences, College of Veterinary Medicine, 4700 Hillsborough St., North Carolina State University, Raleigh, NC 27606. Phone: (919) 513-6234. Fax: (919) 513-6336. E-mail: ed_breitschwerdt{at}ncsu.edu.

Journal of Clinical Microbiology, December 2002, p. 4670-4674, Vol. 40, No. 12
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.12.4670-4674.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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