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Journal of Clinical Microbiology, December 2002, p. 4732-4734, Vol. 40, No. 12
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.12.4732-4734.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Diversity among French Bacillus anthracis Isolates

Agnès Fouet,1 Kimothy L. Smith,2 Chris Keys,2 Josée Vaissaire,3 Claudine Le Doujet,3 Martine Lévy,1 Michèle Mock,1 and Paul Keim2*

Toxines et Pathogénie Bactériennes (CNRS URA 2172), Institut Pasteur, Paris,1 Zoonoses Bactériennes, AFSSA/LERPAZ, Maisons-Alfort, France,3 Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona 86011-56402

Received 2 April 2002/ Returned for modification 1 July 2002/ Accepted 5 August 2002

While outbreaks of animal anthrax zoonoses still regularly occur in France, little is known about the epidemiology links between them. We have used the eight-locus multilocus variable-number tandem repeat analysis typing technique against a collection of 50 Bacillus anthracis isolates from France. There were eight distinct genotypes belonging to two dissimilar genetic clusters. Regional strain patterns were observed, with the B2 genotypes prevalent in southern France and the A1a genotypes found only in northern France.


* Corresponding author. Mailing address: Department of Biological Sciences, Northern Arizona University, Flagstaff, AZ 86011-5640. Phone: (928) 523-1078. Fax: (928) 523-0639. E-mail: Paul.Keim{at}NAU.EDU.


Journal of Clinical Microbiology, December 2002, p. 4732-4734, Vol. 40, No. 12
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.12.4732-4734.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.




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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 2002 by the American Society for Microbiology. All rights reserved.