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Journal of Clinical Microbiology, December 2002, p. 4748-4749, Vol. 40, No. 12
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.12.4748-4749.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

New Technique (the NOW Test) for Rapid Detection of Streptococcus pneumoniae in the Nasopharynx

Howard Faden,* Michael Heimerl, Gail Goodman, Peter Winkelstein, and Chelikani Varma

Department of Pediatrics, State University of New York, University of Buffalo, and Children's Hospital of Buffalo, Buffalo, New York

Received 22 April 2002/ Accepted 26 September 2002

Although the NOW test was originally introduced as a rapid pneumococcal antigen detection test for use with urine samples, it was successfully adapted to nasopharyngeal samples in the present study. The sensitivity, specificity, positive predictive value, and negative predictive value of the test were 92.2, 97.7, 95.9, and 95.5%, respectively. These results demonstrate that nasopharyngeal colonization with Streptococcus pneumoniae can be documented within 15 min of sample collection.

* Corresponding author. Mailing address: Division of Infectious Diseases, Children's Hospital, 219 Bryant St., Buffalo, NY 14222. Phone: (716) 878-7161. Fax: (716) 888-3804. E-mail: hfaden{at}upa.chob.edu.

Journal of Clinical Microbiology, December 2002, p. 4748-4749, Vol. 40, No. 12
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.12.4748-4749.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Gisselsson-Solen, M., Bylander, A., Wilhelmsson, C., Hermansson, A., Melhus, A. (2007). The Binax NOW Test as a Tool for Diagnosis of Severe Acute Otitis Media and Associated Complications. J. Clin. Microbiol. 45: 3003-3007 [Abstract] [Full Text]  
  • Murdoch, D. R., Reller, L. B., Faden, H. (2003). Immunochromatographic Test for Rapid Detection of Streptococcus pneumoniae in the Nasopharynx. J. Clin. Microbiol. 41: 2271-2271 [Full Text]  


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