This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Iturriza-Gómara, M.
Right arrow Articles by Gray, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Iturriza-Gómara, M.
Right arrow Articles by Gray, J.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, December 2002, p. 4797-4799, Vol. 40, No. 12
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.12.4797-4799.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Rotavirus Gastroenteritis and Central Nervous System (CNS) Infection: Characterization of the VP7 and VP4 Genes of Rotavirus Strains Isolated from Paired Fecal and Cerebrospinal Fluid Samples from a Child with CNS Disease

M. Iturriza-Gómara,1,{dagger} I. A. Auchterlonie,2 W. Zaw,2 P. Molyneaux,3 U. Desselberger,1 and J. Gray1*

Clinical Microbiology and Public Health Laboratory, Addenbrooke's Hospital, Cambridge,1 Department of Medical Paediatrics, The Royal Aberdeen Children's Hospital,2 Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom3

Received 9 April 2002/ Accepted 19 August 2002

Rotavirus RNA was detected in the cerebrospinal fluid (CSF) of a child with central nervous system disease symptoms associated with rotavirus gastroenteritis. The rotavirus isolates from the fecal and CSF samples were genotyped as G1P[8]. Sequence analysis of the VP7 and VP4 proteins derived from the fecal and CSF samples were remarkably similar to each other and to G1P[8] rotavirus strains commonly circulating in the community and associated with gastroenteritis.

* Corresponding author. Present address: Enteric Virus Unit, Enteric, Respiratory and Neurological Virus Laboratory, Central Public Health Laboratory, 61 Colindale Ave., London NW9 5HT, United Kingdom. Phone: 44-(0)20 8200 4400. Fax: 44-(0)20 8205 8195. E-mail: Jgray1{at}phls.org.uk.

{dagger} Present address: Enteric Virus Unit, Enteric Respiratory and Neurological Virus Laboratory, Central Public Health Laboratory, London, United Kingdom.

Journal of Clinical Microbiology, December 2002, p. 4797-4799, Vol. 40, No. 12
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.12.4797-4799.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • DiFazio, M. P., Braun, L., Freedman, S., Hickey, P. (2007). Rotavirus-Induced Seizures in Childhood. J Child Neurol 22: 1367-1370 [Abstract]  
  • Graham, K. L., O'Donnell, J. A., Tan, Y., Sanders, N., Carrington, E. M., Allison, J., Coulson, B. S. (2007). Rotavirus Infection of Infant and Young Adult Nonobese Diabetic Mice Involves Extraintestinal Spread and Delays Diabetes Onset. J. Virol. 81: 6446-6458 [Abstract] [Full Text]  
  • Committee on Infectious Diseases, (2007). Prevention of Rotavirus Disease: Guidelines for Use of Rotavirus Vaccine. Pediatrics 119: 171-182 [Abstract] [Full Text]  
  • Blutt, S. E., Fenaux, M., Warfield, K. L., Greenberg, H. B., Conner, M. E. (2006). Active viremia in rotavirus-infected mice.. J. Virol. 80: 6702-6705 [Abstract] [Full Text]  
  • Graham, K. L., Fleming, F. E., Halasz, P., Hewish, M. J., Nagesha, H. S., Holmes, I. H., Takada, Y., Coulson, B. S. (2005). Rotaviruses interact with {alpha}4{beta}7 and {alpha}4{beta}1 integrins by binding the same integrin domains as natural ligands. J. Gen. Virol. 86: 3397-3408 [Abstract] [Full Text]  
  • Boshuizen, J. A., Rossen, J. W. A., Sitaram, C. K., Kimenai, F. F. P., Simons-Oosterhuis, Y., Laffeber, C., Buller, H. A., Einerhand, A. W. C. (2004). Rotavirus Enterotoxin NSP4 Binds to the Extracellular Matrix Proteins Laminin-{beta}3 and Fibronectin. J. Virol. 78: 10045-10053 [Abstract] [Full Text]  
  • Mossel, E. C., Ramig, R. F. (2003). A Lymphatic Mechanism of Rotavirus Extraintestinal Spread in the Neonatal Mouse. J. Virol. 77: 12352-12356 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»