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Journal of Clinical Microbiology, March 2002, p. 1071-1072, Vol. 40, No. 3
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.3.1071-1072.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Comparative Performance of Herpes Simplex Virus Type 1-Specific Serologic Assays from MRL and Meridian Diagnostics

Julie A. Ribes,1,2* Angela Smith,1,2 Marie Hayes,1,{dagger} Doris J. Baker,1 and Jeffrey L. Winters2,{ddagger}

Department of Clinical Sciences,1 Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, Kentucky 40536-02982

Received 17 August 2001/ Returned for modification 11 November 2001/ Accepted 22 December 2001

Two companies, MRL and Meridian Diagnostics, have developed Food and Drug Administration-approved herpes simplex virus type 1 type-specific enzyme immunoassays. The sensitivity, specificity, and overall testing efficiency of these assays were 98.2, 93.8, and 96.6% for MRL and 98.8, 99.0, and 98.1% for Meridian, making both of these kits suitable for use in the clinical lab.

* Corresponding author: Mailing address: University of Kentucky, Department of Pathology and Laboratory Medicine, MS-117 Medical Center, 800 Rose St., Lexington, KY 40536-0298. Phone: (859) 323-1368. Fax: (859) 323-5054. E-mail: jaribes{at}uky.edu.

{dagger} Present address: Boston I. V. F., Waltham, MA 02451.

{ddagger} Present address: The Mayo Clinic, Rochester, MN 55905.

Journal of Clinical Microbiology, March 2002, p. 1071-1072, Vol. 40, No. 3
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.3.1071-1072.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 2002 by the American Society for Microbiology. All rights reserved.