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Journal of Clinical Microbiology, March 2002, p. 799-804, Vol. 40, No. 3
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.3.799-804.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Extended-Spectrum ß-Lactamase-Producing Klebsiella pneumoniae in a Neonatal Intensive Care Unit in the High-Prevalence Area of Athens, Greece

E. Lebessi,1 H. Dellagrammaticas,2 P. T. Tassios,3 L. S. Tzouvelekis,3 S. Ioannidou,1 M. Foustoukou,1 and N. J. Legakis3*

Department of Microbiology,1 Neonatal Intensive Care Unit, P. & A. Kyriakou Children's Hospital,2 Department of Microbiology, Medical School, University of Athens, Athens, Greece3

Received 30 July 2001/ Returned for modification 22 September 2001/ Accepted 12 December 2001

Extended-spectrum ß-lactamase-producing Klebsiella pneumoniae (EPKP) strains are frequently implicated in outbreaks in neonatal intensive care units (NICUs). During the period from 1997 to 1998, 21 infections and 23 colonizations with EPKP were recorded in the NICU of a children's hospital in Athens, Greece. Seventeen of the infected and 12 of the colonized neonates had been referred from other hospitals. The remaining infections and colonizations occurred during the current hospitalization. Pulsed-field gel electrophoresis typing showed that the latter cases were due to an outbreak strain that persisted in the unit, while the repeated introduction of EPKP carriers was mostly due to clonal outbreaks in two maternity hospitals.

* Corresponding author. Mailing address: Department of Microbiology, Medical School, University of Athens, Asias 75, Athens 11527, Greece. Phone: 30-1-7462011. Fax: 30-1-7462124. E-mail: nlegakis{at}med.uoa.gr.

Journal of Clinical Microbiology, March 2002, p. 799-804, Vol. 40, No. 3
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.3.799-804.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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