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Journal of Clinical Microbiology, April 2002, p. 1518-1521, Vol. 40, No. 4
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.4.1518-1521.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Evaluation of the Abbott LCx Quantitative Assay for Measurement of Human Immunodeficiency Virus RNA in Plasma

Carmen de Mendoza,1 José Alcamí,2 María Sainz,3 Dolores Folgueira,2 and Vincent Soriano1*

Service of Infectious Diseases, Hospital Carlos III, Instituto de Salud Carlos III,1 Service of Microbiology, Hospital Doce de Octubre,2 Abbott Laboratories, Madrid, Spain3

Received 4 June 2001/ Returned for modification 23 October 2001/ Accepted 6 December 2001

Plasma human immunodeficiency virus RNA in 491 clinical specimens was measured by LCx. There was a strong correlation with the results provided by other methods (r2 values of 0.93 with Cobas-Monitor version 1.5 and of 0.95 with Quantiplex version 3.0). However, values were uniformly higher with LCx than with Quantiplex when non-B subtypes were tested.

* Corresponding author. Mailing address: C/Nueva Zelanda 54, 4° B, 28035 Madrid, Spain. Phone: 34 91 4532661. Fax: 34 91 7336614. E-mail: vsoriano{at}dragonet.es.

Journal of Clinical Microbiology, April 2002, p. 1518-1521, Vol. 40, No. 4
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.4.1518-1521.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 2002 by the American Society for Microbiology. All rights reserved.