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Journal of Clinical Microbiology, April 2002, p. 1555-1557, Vol. 40, No. 4
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.4.1555-1557.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Probable Mother-to-Infant Transmission of Pneumocystis carinii f. sp. hominis Infection

Robert F. Miller,1 Helen E. Ambrose,2 Vas Novelli,3 and Ann E. Wakefield2*

Department of Sexually Transmitted Diseases, Windeyer Institute of Medical Sciences, Royal Free and University College Medical School, University College,1 Department of Infectious Diseases, Host Defence Unit, Great Ormond Street Hospital for Children, London,3 Infectious Molecular Group Diseases, Department of Paediatrics, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom2

Received 5 November 2001/ Returned for modification 14 December 2001/ Accepted 13 January 2002

A mother and her 4.5-week-old infant had Pneumocystis carinii pneumonia contemporaneously. Genotyping of P. carinii f. sp. hominis DNA at three independent loci showed the same genotype in samples from mother and infant. These data suggest transmission of P. carinii organisms from the mother to her infant.


* Corresponding author. Mailing address: Molecular Infectious Diseases Group, Department of Paediatrics, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, United Kingdom. Phone: 44-1865-222344. Fax: 44-1865-222626. E-mail: wakefiel{at}molbiol.ox.ac.uk.


Journal of Clinical Microbiology, April 2002, p. 1555-1557, Vol. 40, No. 4
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.4.1555-1557.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.




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