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Performance Characteristics of VIDAS and Directigen Respiratory Syncytial Virus (RSV) Antigen Detection Assays and Culture for the Identification of RSV in Respiratory Specimens

Department of Pathology and Laboratory Medicine,¹ University of Kentucky Hospital, University of Kentucky, Lexington, Kentucky 40536-0293²

Received 6 November 2001/ Returned for modification 28 November 2001/ Accepted 10 February 2002

In a comparison of the Directigen and VIDAS respiratory syncytial virus antigen detection assays with viral culture, the sensitivity, specificity, positive and negative predictive values, and testing efficiency were 86, 93.1, 82.7, 94.6, and 91.2% for Directigen; 96.1, 90.8, 80.3, 98.3, and 92.3% for VIDAS; and 88.2, 100, 100, 95.7, and 96.8% for viral culture, respectively.

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