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Journal of Clinical Microbiology, May 2002, p. 1845-1847, Vol. 40, No. 5
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.5.1845-1847.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Molecular Diagnosis of Granulicatella elegans on the Cardiac Valve of a Patient with Culture-Negative Endocarditis

J. P. Casalta,1 G. Habib,2 B. La Scola,1 M. Drancourt,1 T. Caus,3 and D. Raoult1*

Unité des Rickettsies, CNRS UMR 6020, IFR 48, Université de la Méditerranée, Faculté de Médecine, 13385 Marseille cedex 05,1 Service de Cardiologie,2 Service de Chirurgie Cardiaque, Hôpital de la Timone, Marseille, France3

Received 26 November 2001/ Returned for modification 11 January 2002/ Accepted 5 February 2002

We herein report one case of culture-negative infectious endocarditis (IE) where the organism, Granulicatella elegans, was identified by molecular analysis using broad-range PCR primers complementary to the 16S rRNA gene on the removed valve. The results and utility of this method are discussed.

* Corresponding author. Mailing address: Unité des Rickettsies, CNRS UMR 6020, IFR 48, Université de la Méditerranée, Faculté de Médecine, 27 boulevard Jean Moulin, 13385 Marseille cedex 05, France. Phone: (33) 4 91 32 43 75. Fax: (33) 4 91 83 03 90. E-mail: Didier.Raoult{at}medecine.univ-mrs.fr.

Journal of Clinical Microbiology, May 2002, p. 1845-1847, Vol. 40, No. 5
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.5.1845-1847.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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  • Ohara-Nemoto, Y., Kishi, K., Satho, M., Tajika, S., Sasaki, M., Namioka, A., Kimura, S. (2005). Infective Endocarditis Caused by Granulicatella elegans Originating in the Oral Cavity. J. Clin. Microbiol. 43: 1405-1407 [Abstract] [Full Text]  
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