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Journal of Clinical Microbiology, May 2002, p. 1854-1857, Vol. 40, No. 5
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.5.1854-1857.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Microsatellite Characterization of Plasmodium falciparum from Cerebral and Uncomplicated Malaria Patients in Southern Vietnam

Marcelo U. Ferreira,1* Shalini Nair,2 Thien Van Hyunh,3 Fumihiko Kawamoto,4 and Timothy J. C. Anderson2

Department of Parasitology, Institute for Biomedical Sciences, University of São Paulo, 05508-900 São Paulo, Brazil,1 Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas,2 Intensive Care Unit, Lam Dong Provincial Hospital No. 2, Bao Loc, Lam Dong Province, Vietnam,3 Department of International Health, Nagoya University School of Medicine, Nagoya 466-8550, Japan4

Received 28 September 2001/ Returned for modification 12 November 2001/ Accepted 4 December 2001

If parasite genotype influences the clinical course of malaria, we expect that isolates from patients with similar pathology would be more closely related than would be expected by chance. To explore this prediction, we typed nine microsatellite markers in sympatric Plasmodium falciparum isolates from cerebral and uncomplicated malaria patients from Vietnam. Temporal structure and linkage disequilibrium were also examined in this data set.

* Corresponding author. Mailing address: Department of Parasitology, Institute for Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes 1374, 05508-900 São Paulo (SP), Brazil. Phone: 55 11 38187273. Fax: 55 11 38187417. E-mail: muferrei{at}usp.br.

Journal of Clinical Microbiology, May 2002, p. 1854-1857, Vol. 40, No. 5
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.5.1854-1857.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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Copyright © 2002 by the American Society for Microbiology. All rights reserved.