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Journal of Clinical Microbiology, May 2002, p. 1862-1865, Vol. 40, No. 5
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.5.1862-1865.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Pneumocystis carinii f. sp. hominis Is Not Infectious for SCID mice

Isabelle Durand-Joly,1,2* El Moukhtar Aliouat,1,3 Céline Recourt,1 Karine Guyot,1 Nadine François,2 Michèle Wauquier,2 Daniel Camus,1,2 and Eduardo Dei-Cas1,2

Ecologie du Parasitisme, Institut Pasteur de Lille, BP 245, 59019 Lille,1 Parasitologie-Mycologie, Faculté de Médecine et Centre Hospitalier Régional et Universitaire de Lille, 59045 Lille,2 Laboratoire de Parasitologie, Faculté de Pharmacie, BP 83, 59006 Lille, France3

Received 12 November 2001/ Returned for modification 8 January 2002/ Accepted 25 February 2002

The infectious power of Pneumocystis carinii f. sp. hominis was explored by inoculating SCID mice intranasally with either P. carinii f. sp. hominis or P. carinii f. sp. muris isolates. Only mice inoculated with mouse parasites developed Pneumocystis pneumonia, as assessed by microscopy and PCR. These results suggest that humans do not contract pneumocystosis from animals.


* Corresponding author. Mailing address: Ecology of Parasitism, Institute Pasteur of Lille, 1 rue du Prof-Calmette-BP245, 59019 Lille, France. Phone: 33 3 20 87 71 55. Fax: 33 3 20 87 79 08 or 33 3 20 44 42 64. E-mail: isabelle.joly{at}pasteur-lille.fr.


Journal of Clinical Microbiology, May 2002, p. 1862-1865, Vol. 40, No. 5
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.5.1862-1865.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.




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