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Journal of Clinical Microbiology, May 2002, p. 1866-1868, Vol. 40, No. 5
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.5.1866-1868.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Epidemiological Dynamics of Hepatitis C Virus among 747 German Individuals: New Subtypes on the Advance

Matthias Schröter,1 Bernhard Zöllner,1 Peter Schäfer,1 Andreas Reimer,2 Matthias Müller,3 Rainer Laufs,1 and Heinz-Hubert Feucht1*

Institut für Medizinische Mikrobiologie und Immunologie, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg,1 Fachklinik Villa unter den Linden, 65913 Frankfurt/Main,2 Gemeinschaftspraxis Drs. Müller/Wollenweber, 65931 Frankfurt-Sindlingen, Germany3

Received 28 September 2001/ Returned for modification 23 January 2002/ Accepted 13 February 2002

This study demonstrates the dynamics in the epidemiology of hepatitis C virus subtypes. Subtypes 3a and 4a have become increasingly prevalent in patients where an infection within recent years can be assumed. Evidence is presented that the subtypes observed among younger patients can spread rapidly and lead to significant changes in the subtype distribution.

* Corresponding author. Mailing address: Institut für Medizinische Mikrobiologie und Immunologie, Universitätsklinikum Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany. Phone: 49 (0)40 42803 3159. Fax: 49 (0)40 42803 4062. E-mail: feucht{at}uke.uni-hamburg.de.

Journal of Clinical Microbiology, May 2002, p. 1866-1868, Vol. 40, No. 5
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.5.1866-1868.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
Clin. Vaccine Immunol. ALL ASM JOURNALS

Copyright © 2002 by the American Society for Microbiology. All rights reserved.