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Journal of Clinical Microbiology, June 2002, p. 2249-2250, Vol. 40, No. 6
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.6.2249-2250.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Vancomycin Susceptibility of Oxacillin-Resistant Staphylococcus aureus Isolates Causing Nosocomial Bloodstream Infections

Sandra M. Tallent,1* Tammy Bischoff,1 Michael Climo,1,2 Belinda Ostrowsky,1 Richard P. Wenzel,1 and Michael B. Edmond1

Department of Internal Medicine, Medical College of Virginia Campus of Virginia Commonwealth University,1 Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond, Virginia2

Received 19 December 2001/ Returned for modification 29 January 2002/ Accepted 1 March 2002

Nosocomial oxacillin-resistant Staphylococcus aureus (ORSA) bloodstream isolates were tested to determine the prevalence of vancomycin heteroresistance. We screened 619 ORSA nosocomial bloodstream isolates from 36 hospitals between 1997 and 2000. Only one isolate exhibiting heterotypic resistance was detected. Thus, vancomycin heteroresistance in clinical bloodstream isolates remains rare in the United States.


* Corresponding author. Mailing address: Virginia Commonwealth University, P.O. Box 980019, Richmond, VA 23298. Phone: (804) 827-0725. Fax: (804) 828-3602. E-mail: smtallen{at}hsc.vcu.edu.


Journal of Clinical Microbiology, June 2002, p. 2249-2250, Vol. 40, No. 6
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.6.2249-2250.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.




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