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Journal of Clinical Microbiology, July 2002, p. 2651-2652, Vol. 40, No. 7
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.7.2651-2652.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Prevalence of the fsr Locus in Enterococcus faecalis Infections

S. K. Pillai,* G. Sakoulas, H. S. Gold, C. Wennersten, G. M. Eliopoulos, R. C. Moellering, Jr., and R. T. Inouye

Division of Infectious Diseases, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02115

Received 12 February 2002/ Accepted 21 April 2002

The fsr locus of Enterococcus faecalis confers virulence in animal models. A retrospective analysis of fsr prevalence in diverse E. faecalis clinical isolates demonstrated fsr in all endocarditis isolates versus 53% of stool isolates (P = 0.005). This supports a role for fsr-mediated virulence in the pathogenesis of enterococcal infections in humans.

* Corresponding author: Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Institutes of Medicine Bldg., Room 219, 4 Blackfan Cir., Boston, MA 02115. Phone: (617) 667-0046. Fax: (617) 975-5235. E-mail: spillai{at}caregroup.harvard.edu.

Journal of Clinical Microbiology, July 2002, p. 2651-2652, Vol. 40, No. 7
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.7.2651-2652.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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