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Journal of Clinical Microbiology, July 2002, p. 2675-2676, Vol. 40, No. 7
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.7.2675-2676.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Prevalence of Helicobacter pylori in Sri Lanka as Determined by PCR

N. Fernando,1 J. Holton,1* D. Vaira,2 M. DeSilva,3 and D. Fernando3

Department of Bacteriology, Royal Free & University College London Medical School, London, United Kingdom,1 First Medical Clinic, University of Bologna, Bologna, Italy,2 Department of Surgery, Faculty of Medical Sciences, University of Sri Jayewardena, Colombo, Sri Lanka3

Received 21 February 2001/ Returned for modification 14 May 2001/ Accepted 23 April 2002

Fifty-seven Sinhalese patients were investigated for the presence of Helicobacter pylori by PCR. A prevalence of 70.1%, with 47.5% positive for cagA, was demonstrated. The most common vacA allele was s1am1. There was no significant association between either the s1 allele or the cagA allele and severe gastroduodenal disease. There was an association between the s1 allele and the cagA locus.


* Corresponding author. Mailing address: Department of Bacteriology RF&UCLMS Windeyer Institute of Medical Sciences, 46 Cleveland St., London W1P 7PB, United Kingdom. Phone: 20 7504 9485. Fax: 20 7636 8175. E-mail: j.holton{at}ucl.ac.uk.


Journal of Clinical Microbiology, July 2002, p. 2675-2676, Vol. 40, No. 7
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.7.2675-2676.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.




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Copyright © 2002 by the American Society for Microbiology. All rights reserved.