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Journal of Clinical Microbiology, August 2002, p. 3035-3037, Vol. 40, No. 8
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.8.3035-3037.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Isolation from a Healthy Carrier and Characterization of a Neisseria meningitidis Strain That Is Deficient in {gamma}-Glutamyl Aminopeptidase Activity

Hideyuki Takahashi,1 Hiroshi Tanaka,2 Hiroo Inouye,2 Toshiro Kuroki,3 Yuko Watanabe,3 Shiro Yamai,3 and Haruo Watanabe1*

Department of Bacteriology, National Institute of Infectious Diseases, Tokyo,1 Department of Bacteriology, Ehime Prefectural Institute of Public Health and Environmental Science, Matsuyama,2 Department of Bacteriology and Pathology, Kanagawa Prefectural Public Health Laboratory, Yokohama, Japan3

Received 27 December 2001/ Returned for modification 22 April 2002/ Accepted 1 May 2002

{gamma}-Glutamyl aminopeptidase (GGT) activity is used as a specific marker for the identification of Neisseria meningitidis. We isolated from a healthy carrier and characterized an N. meningitidis isolate which lacked the activity due to the insertional mutation of the ggt gene, suggesting that naturally occurring N. meningitidis isolates do not always possess GGT activity.

* Corresponding author. Mailing address: Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1-23-1, Shinjuku-ku, Tokyo, 162-8640, Japan. Phone: 81-3-5285-1111(-2201). Fax: 81-3-5285-1171. E-mail: haruwata{at}nih.go.jp.

Journal of Clinical Microbiology, August 2002, p. 3035-3037, Vol. 40, No. 8
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.8.3035-3037.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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