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Journal of Clinical Microbiology, August 2002, p. 3057-3059, Vol. 40, No. 8
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.8.3057-3059.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

DNA Hybridization Test: Rapid Diagnostic Tool for Excluding Bacterial Vaginosis in Pregnant Women with Symptoms Suggestive of Infection

Armin Witt, Ljubomir Petricevic, Ulrike Kaufmann, Hubertus Gregor, and Herbert Kiss*

Department of Obstetrics and Gynecology, University of Vienna Medical School, Vienna, Austria

Received 19 February 2002/ Returned for modification 23 April 2002/ Accepted 29 May 2002

This prospective comparative study evaluated a DNA hybridization test (Affirm VPIII) as an alternative to Gram stain for the diagnosis of bacterial vaginosis. We examined vaginal smears from 1,725 pregnant women between the 12th and 36th weeks of gestation with clinical signs of vaginal infection. The DNA hybridization test compared well with Gram stain and can be used as a rapid diagnostic tool to exclude bacterial vaginosis.

* Corresponding author. Mailing address: Department of Obstetrics and Gynecology, University of Vienna Medical School, Währinger Gürtel 18-20, A-1090 Vienna, Austria. Phone: 43-1-40400-2822. Fax: 43-1-40400-2861. E-mail: herbert.kiss{at}akh-wien.ac.at.

Journal of Clinical Microbiology, August 2002, p. 3057-3059, Vol. 40, No. 8
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.8.3057-3059.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.





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Antimicrob. Agents Chemother. Clin. Microbiol. Rev.
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Copyright © 2002 by the American Society for Microbiology. All rights reserved.