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Journal of Clinical Microbiology, August 2002, p. 3071-3075, Vol. 40, No. 8
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.8.3071-3075.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Corneal Ulcer Caused by the New Fungal Species Sarcopodium oculorum

Josep Guarro,1,2* Ana Luisa Höfling-Lima,3 Josepa Gené,1,2 Denise De Freitas,3 Patricio Godoy,4 Maria Luisa Zorat-Yu,3 Luis Zaror,5 and Olga Fischman4

Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut,1 Institut d'Estudis Avançats, Universitat Rovira i Virgili, 43201 Reus, Tarragona, Spain,2 Disciplina de Oftalmología,3 Disciplina de Biología Celular, UNIFESP/EPM, São Paulo, Brazil,4 Instituto de Microbiología Clínica, Universidad Austral de Chile, Valdivia, Chile5

Received 11 February 2002/ Returned for modification 9 April 2002/ Accepted 8 May 2002

We describe a case of keratitis caused by a new species of the hyphomycetous genus Sarcopodium, S. oculorum. The corneal ulcer developed after 5 months of treatment with corticosteroids in a Brazilian boy diagnosed with allergic conjunctivitis. Fungal hyphae and conidia were detected in corneal scrapings, and repeated cultures were positive for this fungus. The infection was resolved with natamycin and ketoconazole. Eleven antifungals were tested against this fungus, and all except flucytosine and fluconazole showed in vitro activity.

* Corresponding author. Mailing address: Unitat de Microbiologia, Departament de Ciències Mèdiques Bàsiques, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Carrer Sant Llorenç 21, 43201 Reus, Tarragona, Spain. Phone: 34 977759359. Fax: 34 977759322. E-mail: umb{at}fmcs.urv.es.

Journal of Clinical Microbiology, August 2002, p. 3071-3075, Vol. 40, No. 8
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.8.3071-3075.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

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  • Guarro, J., Rubio, C., Gene, J., Cano, J., Gil, J., Benito, R., Moranderia, M. J., Miguez, E. (2003). Case of Keratitis Caused by an Uncommon Fusarium Species. J. Clin. Microbiol. 41: 5823-5826 [Abstract] [Full Text]  
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