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Journal of Clinical Microbiology, September 2002, p. 3489-3492, Vol. 40, No. 9
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.9.3489-3492.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Increasing Incidence of Candidemia: Results from a 20-Year Nationwide Study in Iceland

University of Iceland, Reykjavik 101Departments of,¹ Clinical Microbiology,² Internal Medicine, Landspitali University Hospital, Reykjavik 108, Iceland³

Received 25 January 2002/ Returned for modification 29 March 2002/ Accepted 27 June 2002

A nationwide study on candidemia was conducted in Iceland from 1980 to 1999. The annual incidence increased from 1.4 cases/100,000 inhabitants/year between 1980 and 1984 to 4.9 cases/100,000 inhabitants/year between 1995 and 1999 (P < 0.0001). Candidemia episodes at university hospitals increased from 0.15/1,000 admissions to 0.55/1,000 admissions (P < 0.0001). Candida albicans was the predominant species responsible (64.4%). The national import of fluconazole increased approximately fourfold during the second half of the study, but increased resistance to this agent was not observed.

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